Sheryl Crow Announces Summer 'De-Tour' & other

Tuesday 2 September 2008

Gene Therapy Anti Cancer Work Featured In Scientific American

�Scientific American magazine focused on two University of Alabama at Birmingham (UAB) Comprehensive Cancer Center researchers in a news story on observational next-generation anticancer therapies.

David T. Curiel, M.D., Ph.D., is a UAB professor of medicine and director of the human gene therapy division, and Ronald Alvarez, M.D., is a UAB professor of medicine and director of the gynecologic oncology division.

Both doctors ar featured in a Scientific American particular cancer edition, and both served as co-authors on the account "Tumor-busting viruses." The editors chose Curiel and Alvarez because of their research into a field call viral factor therapy, or virotherapy.

Virotherapy involves an experimental technique to target viruses to genus Cancer cells spell leaving levelheaded cells unaffected. The viruses are genetically engineered to kill tumor cells in different ways. One means is by adopting the viruses' natural ability to invade and reproduce as a way to deliver target genes that make tumor cells more susceptible to existing chemotherapies.

Curiel and Alvarez have been testing this concept with a virus compound called adenovirus in women with repeated ovarian or other gynecologic cancers. The clinical trial is noneffervescent in the early stages, yet the compound has shown antitumour effects that appear secure to most patients, Curiel said.

"We foresee a strong role for viruses that is, curative viruses in 21st-century medicament," Curiel and Alvarez wrote in wrote in the story.

First proposed in the 1940s, virotherapy now relies heavily on adenoviruses, a cause of the common cold that has been studied and altered extensively for medical research. Adenoviruses have the ability to shuttle targeted segments of DNA into a tumor cell and make biochemical changes that minimize damage to good for you cells.

University of Alabama at Birmingham

701 20th St. S, AB 1320

Birmingham, AL 35294-0113

United States
http://www.uab.edu

More info

Wednesday 13 August 2008

`Dark Knight' stays on top with $26M

LOS ANGELES �

Batman was higher than Hollywood's newest bay window heads.

"The Dark Knight" took in $26 million to finish as the No. 1 picture for the fourth straight weekend, beating the stoner comedy "Pineapple Express," which opened in second

Wednesday 6 August 2008

'Watchmen' Scenes Of War, Murder And Transformation Draws Thunderous Response At Comic-Con

SAN DIEGO — If day unitary of Comic-Con belonged to "Twilight," then the sec afternoon, still filled with scantily clad Leias and obese Batmen, was the realm of "Watchmen." A comic book holy grail for 3 decades, the Alan Moore/ Dave Gibbons masterpiece is the only if graphic novel ever to win skill fiction's honored Hugo Award and the only comic to appear in Time magazine's list of the greatest novels of the 20th century. This supposedly unfilmable flux of ism, theology and heroism has caused such names as Gilliam, Aronofsky and Greengrass to throw their custody up in disgust.

But on Friday — one year after

Thursday 26 June 2008

Die My Demon

Artist: Die My Demon

   Genre(s):
Other

Discography:

Still Loving The Game

Year: 2004
Tracks: 14

Wednesday 18 June 2008

Metronomy announce one-off London show

Metronomy have announced a one-off London show, set to take place in July.

The group, led by songwriter and multi-instrumentalist Joseph Mount, will play Camden's Barfly on July 2.

The gig comes shortly before Metronomy release their new single 'Holiday' on July 7.

The band's album 'Nights Out', a concept record about going out, is set to be released on September 8.

To check the availability of Metronomy tickets and get all the latest listings, go to NME.COM/GIGS now, or call 0871 230 1094.

Monday 9 June 2008

Matchbox twenty's guitarist steps in front of the microphone with new band

LOS ANGELES - Paul Doucette's experience as one part of the hugely successful matchbox twenty taught him a little something about the break and repair method of music-making.

Not too long ago, Doucette along with other band mates wondered if matchbox twenty would have a future. After years of friction, the band took an extended hiatus with some wondering if they would ever regroup.

It was during that time Doucette put together the group The Break and Repair Method, stepping in front of the microphone as their lead songwriter and singer.

"It was a product of definitely being in a band and being in a band where I wasn't a songwriter," Doucette said in an interview announcing both the band and its new album. "It was an experiment: What do I sound like on my own?"

The result, he says, is "milk the bee," the anticipated debut album from The Break and Repair Method set to be released this fall. The first single, "You Won't Be Able To Be Sad," drops later this month.

It's an album, Doucette says, that almost didn't make it after going through three different labels before finding a home with bluhammock music.

"The title came out of that frustration: Putting out a record is like milking a bee. It's pointless," he said.

It's an album that appears also to have been born out of musical frustration.

"It kind of started as a mine, mine, mine thing," he said.

It has since grown to include a number of musicians and singers, including his wife Moon Zappa, who sings on several tracks.

A first listen to the album reveals that is a musical departure from matchbox twenty.

From the first single to the last song, recently added, "The City (Is Bound To Do Us In)," Doucette's affinity for dark lyrics set to upbeat melodies is evident. But it's his sometimes bluesy, gravelly vocals that drive it home.

Doucette says he doesn't expect to have an explosive solo career, like matchbox's lead singer Rob Thomas.

"I don't expect people to go 'Oh, he's in matchbox. I love his record,' " he said. "They don't know me. They know me as matchbox twenty."

Since the completion of "milk the bee," Doucette has been making music again with his friends in what some may call a repaired matchbox twenty. He also switched roles in the band, moving from drummer to rhythm guitarist to replace Adam Gaynor, who left the band.

"One of the things that helped us on the matchbox thing is that we all went off and did our own thing," he said.

Doucette said matchbox plans to reunite to put out another album some time in 2009. In the meantime, he plans to tour with The Break and Repair Method.

"In an ideal world, I'll be going back and forth between the two," he said. "That's a good problem to have."

And by the way, he has since learned people really do milk bees. It's a term used to describe the extraction of bee venom.